On Sunday, Cogent Biosciences, Inc. (NASDAQ: COGT ) revealed updated clinical results from the Open Label Extension (OLE) portion of the SUMMIT trial of bezuclastinib in patients with non-advanced systemic mastocytosis .

Non-advanced systemic mastocytosis is a rare disease that involves mast cell buildup in tissues and organs .

Updated clinical data presented at the American Society of Hematology Annual Meeting & Exposition show:

Pharmacodynamic Data: Bezuclastinib showed rapid, deep, and sustained reductions in serum tryptase over 24 weeks of treatment, including:

Safety Data

SUMMIT Enrollment Update

Price Action: COGT stock is up 10.60% at $9.83 at the last check on Monday.

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